منابع مشابه
Heparin and angiogenic therapy.
Collateral circulation is an alternative source of blood supply to the myocardium if this is jeopardized by failure of the original vessel to provide adequate flow. Gradual occlusion, or a high grade stenosis of the coronary arteries, is frequently associated with collateral development in patients with coronary artery disease. Although the existence of collateral circulation in such patients i...
متن کاملAngiogenic efficacy of Heparin on chick chorioallantoic membrane
Heparin is an anticoagulant agent known to have diverse effects on angiogenesis with some reports suggesting that it can induce angiogenesis while a few have indicated of its inhibitory property. Cancer patients treated for venous thromboembolism with low molecular heparin had a better survival than the unfractionated heparin (UFH). Heparin is known to interact with various angiogenic growth fa...
متن کاملComparison of leeching and heparin therapy in management of acute venous congestion of limbs in rat
Acute venous congestion leads to blood stasis in the tissue and impaired blood perfusion. Using medicinal leech is an old method for reducing tissue congestion. There are numerous factors in leech saliva and hirudin that have important roles in the leeching beneficial effect. In this study, an animal study was performed to compare leech therapy with heparin therapy in the treatment of acute ven...
متن کاملTumor angiogenesis and anti-angiogenic therapy.
Anti-angiogenic therapy is an anti-cancer strategy that targets the new vessels that grow to provide oxygen and nutrients to actively proliferating tumor cells. Most of the current anti-cancer reagents used in the clinical setting indiscriminately target all rapidly dividing cells, resulting in severe adverse effects such as immunosuppression, intestinal problems and hai...
متن کاملAnti-Angiogenic Therapy and Cardiovascular Diseases
The process involving new blood vessel sprouting from already existing ones is regulated by a physiological complex mechanism, known as angiogenesis. It plays a key role in wound healing but is also present in pathophysiological conditions such as cancer and cardiovascular disease, which have the highest rates of morbidity and mortality worldwide. It is stimulated mechanically or chemically, wi...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2000
ISSN: 0195-668X
DOI: 10.1053/euhj.1999.1700